Dissection of a neuronal integrator circuit through correlated light and electron microscopy in larval zebrafish. Part 1: Functional imaging and ultrastructure in the same animal
Jonathan Boulanger-Weill, Florian Kämpf, Gregor Schuhknecht, Sumit Vohra, Mariela Petkova, Maren Eberle, Richard Schalek, Filippo Del Bene, Florian Engert, Jeff Lichtman, Armin Bahl · FENS Forum 2024
Accumulating sensory information over long-time scales is a critical component of most circuit computations in the brain across species. It remains poorly understood how such dynamics are implemented mechanistically at the synaptic level. Dissecting such neural circuits in vertebrates requires precise knowledge of functional neural properties and correlating dynamics with the underlying wiring diagram within the same individual animal. Here we combine functional calcium imaging with ultrastructural circuit reconstruction, using a visual motion accumulation task in larval zebrafish. Using conne
ePoster · Neuroscience