ePoster · Behavioral Neuroscience
Contrasting the role of excitatory pyramidal cells and GABAergic interneurons in prefrontal cortex through a novel contextual auditory stimulus task paradigm and calcium imaging
Florian Steenbergen, Brice De La Crompe, Julian Ammer, Ilka Diester · FENS Forum 2024
The prefrontal cortex plays a key role in the representation of cognitive parameters, including task-relevant sensory cues, action selection and context. However, the contribution of GABAergic inhibitory interneuron types to the representation of these task features in active cell assemblies and their formation is incompletely understood. Here we focus specifically on parvalbumin (PVIs) and somatostatin (SOMIs) expressing interneurons within the prelimbic cortex (PL) of mice, as these interneuron types have been described to be involved in context encoding.We designed a contextual-auditory sti