Topic: contextual feedback

Sensory neural representations are modulated by a variety of contextual factors, such as multi-modal cues, stimulus history, novelty, behavioral utility, and internal states. Despite decades of attention in systems neuroscience, many questions persist regarding how sensory codes adapt to these different variables. Here, we study this problem in the olfactory system. We focus on a neural circuit (the bulb) where incoming odor inputs are integrated with extensive contextual feedback from areas of the brain involved in multi-sensory association, attention, memory, and decision- making. While most