Topic: contralesional cortex

Ischemic stroke results from neural tissue death due to a decrease in blood supply, and is a major cause of death and motor disabilities worldwide. Although it is established that the tissue immediately surrounding the stroke core undergoes spontaneous functional reorganization, partially taking over lost functionality, the role of the healthy contralesional cortex remains unclear. Adaptions in neuronal activity on the contralesional side have been reported both in humans and in rodent stroke models, but it remains elusive whether such modifications represent spontaneous functional re-mapping