Topic: controllability gramian

How the brain responds to non-invasive brain stimulation, such as transcranial magnetic stimulation (TMS), depends on the physiological state. In recent years, we have come to understand what happens at the stimulation site, but the whole-brain response remains unclear. Here, we consider the brain as an autonomous control system and stimuli as control inputs, and use the framework of control theory to describe the whole-brain response to brain stimuli. Our method, based on the so-called controllability gramian, can reveal not only the average controllability, i.e. how easily the brain dynamics