Topic: cortex-wide projectome

Cortico-cortical projection neurons bridge functionally distinct brain regions within and between the cortical hemispheres. Determining the logic of this macrocircuitry is necessary for understanding how cortical integration enables high level brain function involving multiple sensory, motor and cognitive processes. To begin to address this, we have performed a systematic anatomical analysis of the interareal organization of the cortex-wide projectome onto the primary visual, somatosensory and motor cortices of adult mice. Using brain-wide retrograde viral tracing followed by serial 2-photon t