Unraveling the impact of architectural complexity on cortical-hippocampal circuit dynamics with brain-on-a-chip models
Martina Brofiga, Francesca Callegari, Fabio Poggio, Ilaria Donati della Lunga, Valerio Barabino, Letizia Cerutti, Mariateresa Tedesco, Paolo Massobrio · FENS Forum 2024
The human brain comprises about 86 billion neurons organized in well-defined spatial locations that define clusters of neurons (modules). Each cognitive and motor function is possible thanks to the correct interaction among them. The disruption, loss, or alteration of these connections can produce pathological conditions. To understand how the information is transmitted and computed, we need to investigate the communication among the different modules. Another essential feature to understand is how the electrophysiological signals are transmitted is the 3D spatial organization. Many studies ma
ePoster · Neuroscience