Topic: cortical arousal

Subplate neurons are among the earliest generated neurons in the cerebral cortex that orchestrate the development of the intra and extracortical connections. A large proportion of these neurons undergoes cell death throughout postnatal development. The remaining cells form the thin and compact cortical layer 6b (L6b) in murine cortex. The functional aspects of L6b have received little attention compared to the other layers. Recent studies have argued that the extensive intracortical connections and cortico-thalamic-cortical loops of L6b neurons might enable sensory processing to extract salien