Cortex-wide high density ECoG recordings from rat reveal diverse generators of sleep-spindles with characteristic anatomical topographies and non-stationary subcycle dynamics
Arash Shahidi, Ramon Garcia-Cortadella, Gerrit Schwesig, Anna Umurzakova, Mudra Deshpande, Ekaterina Sonia, Anton Sirota · Bernstein Conference 2024
Accumulating evidence from electrocorticogram (ECoG) recordings and imaging challenge traditional views of brain oscillations as spatially stationary periodic sources. Understanding the spatio-temporal dynamics of cortical activity requires novel measurement and analysis methodologies. We recorded broadband local field potential (LFP) across the whole neocortex in freely behaving rats using high-density flexible surface arrays using active transistors. 3D tracking and spatio-spectral analysis of recordings over long sessions enabled automatic and accurate brain and behavioral states segmentati