Topic: corticostriatal loops

The mammalian striatum is critically involved in perceptual decision-making, where disrupted dopamine transmission leads to perceptual disturbances such as hallucinations. The precise mechanism by which striatal dopamine contributes to perceptual decisions is not known. We investigated this by developing a circuit model in which perceptual learning and value learning are implemented in parallel corticostriatal loops to inform action selection. Previous models of corticostriatal plasticity have focused primarily on how reward prediction errors signaled by dopamine enable value learning in the v