Hierarchical encoding of reward, effort and choice across the frontal cortex and basal ganglia during cost-benefit decision making
Oliver Haermson, Isaac Grennan, Brook Perry, Robert Toth, Colin G. McNamara, Timothy Denison, Hayriye Cagnan, Sanjay G. Manohar, Mark E. Walton, Andrew Sharott · FENS Forum 2024
Adaptive value-guided decision-making requires weighing up the costs and benefits of pursuing an available opportunity. Though neurons across frontal cortical-basal ganglia circuits have been repeatedly shown to represent decision-related parameters, it is unclear whether and how this information is coordinated. To address this question, we performed large-scale single unit recordings simultaneously across 5 medial/orbital frontal and basal ganglia regions as rats decided whether to pursue varying reward payoffs available at different effort costs. We found that single neurons encoding combina
ePoster · Neuroscience