Topic: Cre-recombinase

The third ventricle in the hypothalamus is lined by specialized glia-like cells called tanycytes. They are highly polarized cells, whose projections reach into different nuclei of the mediobasal hypothalamus and median eminence, responsible for energy homeostasis, food intake, and hormone release. Historically, tanycytes have been distinguished into alpha and beta subtypes according to their morphology and location along the ventricle. However, the classification according to localization alone does not provide information about the function of these cells. Therefore, we modified adeno-associa