A qualitative analysis of the relationship of glutamate and glutamine and metabolic profiling in focal epilepsy using 7T CRT-FID-MRSI
Stefanie Chambers, Haniye Shayeste, Philipp Lazen, Matthias Tomschik, Jonathan Wais, Lukas Hingerl, Bernhard Strasser, Lukas Haider, Gregor Kasprian, Tatjana Traub-Weidinger, Christoph Baumgartner, Johannes Koren, Katharina Moser, Florian Mayer, Martha Feucht, Christian Dorfer, Ekaterina Pataraia, Wolfgang Bogner, Siegfried Trattnig, Karl Rössler, Gilbert Hangel · FENS Forum 2024
Epilepsy, a debilitating illness characterized by seizures, often proves resistant to medication necessitating surgical intervention. Advanced MRI techniques, notably 7T MRI, can offer improved lesion detection. However, patients without structural abnormalities pose a particular challenge. In such cases, 7T Magnetic Resonance Spectroscopy Imaging (MRSI) may prove beneficial in identifying subtle metabolic alterations though higher spectral resolution, allowing the separation of metabolites with overlapping resonance frequencies such as glutamate and glutamine, key metabolites in excitatory pr
ePoster · Neuroscience