Serotonin’s implication in behavioral inhibition as a consequence of involvement in exploration
Stefan Hajduk, Solene Sautory, Davide Crombie, Felix Hubert, Leopoldo Petreanu, Zach Mainen · COSYNE 2025
Serotonin (5-HT) is implicated in decision-making, such as signaling prediction errors and cue values, as well as to the regulation of behavioral states of wakefulness and arousal, but the relationship between these two domains of function is not well understood. On one hand, serotonin activity is negatively associated with locomotor behavior, which has been seen as behavioral inhibition. On the other hand, serotonin transients are also associated with surprise or uncertainty, as well as novelty responses, including exploration-related facial movements (e.g., whisking, sniffing). Because ther
ePoster · Neuroscience