Dendritic mitochondrial transport in mature neurons is important for motor skill learning
Hae-Na Choi, Kristiano Ndoci, Felix Gaedke, Camilla Aurora Franchino, Astrid Schauss, Elisa Motori · FENS Forum 2024
Mitochondrial trafficking is essential for neuronal development as well as for maintenance of functional mitochondrial pools at synaptic terminals. Nevertheless, the relevance of this process for mature neurons and the mechanisms governing the inherent motility of mitochondria across neuronal compartments remains unknown. By imaging mitochondrial transport in developing Purkinje neurons (PN) in situ, we observed progressive the formation of stable pools in the distal regions of dendrites, while larger dendritic calibers and axonal shaft kept a considerable extent of organelle motility up and b
ePoster · Neuroscience