Long-lasting effects of prenatal delta-9-tetrahydrocannabinol exposure in young rat offspring
Serena Di Martino, Martina Di Bartolomeo, Enrico Gugliandolo, Gian Marco Leone, Katia Mangano, Martin Kuchar, Filippo Drago, Fulvio D’Acquisto, Carla Cannizzaro, Claudio D'Addario, Vincenzo Micale · FENS Forum 2024
Consumption of cannabinoid-containing products has increased for their beneficial effects on pregnancy for reducing symptoms such as nausea, vomiting or anxiety. However, FDA clearly strongly advises against the use of delta-9-tetrahydrocannabinol (THC) during pregnancy. Alongside, mostly of the studies have investigated the effects of prenatal THC (pTHC) exposure, in males only, but pTHC shows a sex bias. Here, we investigate the effects of pTHC exposure in the male and female young rats.Sprague and Dawley rats were subcutaneously treated with THC (2 mg/kg/day) or vehicle (VHC), from gestatio
ePoster · Neuroscience