ePoster · Computational Neuroscience
Theta-modulated memory encoding and retrieval in recurrent hippocampal circuits
Samuel Eckmann, Yashar Ahmadian, Máté Lengyel · Bernstein Conference 2024
The hippocampus plays a central role in memory processing. In order to avoid deleterious interference between stored and ongoing experience, theoretical considerations require a separation between phases of memory encoding and recall within the same neural circuit, putatively controlled by hippocampal theta oscillations [1]. However, the neural mechanisms subserving this separation remain unknown. Classical models either remain moot about these mechanisms [2], or assume purpose-built neuromodulatory interactions that are in conflict with biologically realistic timescales of synaptic modulation