Topic: deep layers

Successful navigation requires knowledge of the specific locations of different objects. However, currently only an object-invariant signal was discovered, marking all objects at all locations (carried by object-vector cells in the superficial layers of the medial entorhinal cortex (MEC)). It is thus unknown where and if this general object signal is crossed with a signal for a specific location (as is carried by place cells in the hippocampus), and whether these two variables are encoded conjunctively. We hypothesized that if indeed the brain represents object × position in a conjunctive ma