Lindane toxicity amelioration by delta sleep peptide supplementation: Advanced EEG study
Olivera Stanojlovic, Nikola Šutulović, Željko Grubač, Milena Vesković, Dušan Mladenović, Yavuz Dodurga, Mucahit Seçme, Djuro Macut, Nebojša Radunović, Aleksandra Rašić-Marković, Dragan Hrnčić · FENS Forum 2024
Lindane, gamma hexachlorocyclohexane is organochlorine compound that is environmental pollutant and is used as a pesticide and scabicide even today in a number of undeveloped countries. Lindane induces seizures refractory to conventional antiepileptics. Delta sleep-inducing peptide (DSIP) is an endogenous peptide that is constantly present in several different brain regions showing neuroprotective The aim of our study was to examine the effects of DSIP supplementation on electroencephalographic (EEG) ictal activity induced by lindane in rats. Adult male rats with previously implanted electrode
ePoster · Neuroscience