Topic: dendritic input integration

Non-linear dendritic input integration can greatly boost the computational power of individual neurons. Investigating dendritic population dynamics in regions with sparsely active neurons such as hippocampus using in vivo 2-photon requires calcium imaging of densely labeled preparations. However, current analysis methods face limitations in processing densely labeled dendritic preparations because identification of regions of interest (ROIs) corresponding to individual dendrites and extracting temporal components from overlapping ROIs is difficult. Here we present a method for automatic identi