Topic: depression-like behaviours

Early stress episodes affect brain development and is related to increased risk of developing stress-induced depression in adulthood. However, little is known about the sexual differences in this process. Our goal is to study how stress in different developmental periods affects depression-like behaviours in male and female mice. For this purpose, four experimental groups of both male and female mice of strain C57BL/6J were used: control (C) Juvenile (JE), adult (AE), and double stress JE+AE (DE).Depression-like behaviours were evaluated in the adult period. Nest building test was used to asse