Circulating microRNA: A promising avenue for AD diagnosis and novel therapeutic targets
Agnese Graziosi, Luca Ghelli, Camilla Corrieri, Giulia Sita, Fabiana Morroni, Arianna Pani, Andrea Pilotto, Alessandro Padovani, Patrizia Hrelia · FENS Forum 2024
Alzheimer's Disease (AD) is a complex and progressive neurodegenerative disorder that affects millions of people worldwide. However, current treatments and diagnostic methods are ineffective in early detection and intervention. Recently, researchers have focused on the dysregulation of small non-protein-coding microRNA (miRNA) and the associated post-transcriptional gene alteration in AD. Biofluids, such as serum and cerebrospinal fluid, contain miRNAs that can be identified and quantified. The project aims to identify circulating miRNAs within serum and CSF, which can be used as non-invasive
ePoster · Neuroscience