Perturbing inhibitory activity interferes with memory reactivation and attenuates learning in postrhinal cortex
Kristian Kinden Lensjø, Ingeborg Nymoen, Frederik Sebastian Rogge, Arthur Sugden, Inga Shurnayte, Kristin Tøndel, Sverre Grødem, Torkel Hafting, Mark Andermann, Marianne Fyhn · FENS Forum 2024
Consolidation of salient experiences to form memories rely on precise coupling of high frequency neural network events between hippocampus and neocortex. Within these events, reactivation of subpopulations of neurons is believed to strengthen connections within and between networks. We have previously shown that cue-specific reactivation occurs in postrhinal cortex during learning of a visual association task. Moreover, recent work suggests a role for parvalbumin-expressing (PV) inhibitory interneurons in consolidation by synchronizing hippocampal and cortical activity. We therefore hypothesiz
ePoster · Neuroscience