The pupillary light reflex drives evoked responses in retinal ganglion cells
Pietro Micheli, Tjaša Lapanja, Andres Gonzales, Matteo Tripodi, Hiroki Asari, Santiago Rompani · FENS Forum 2024
Sharp changes in ambient luminance are known to modulate the size of the pupil, regulating the amount of light that enters the eye and reaches the retina. This process, known as pupillary light reflex (PLR), allows the retina to rapidly adapt to different luminance conditions. While PLR has been widely characterized in terms of its neural underpinnings as well as its clinical and behavioral significance, one simple question is still pending: does PLR directly modulate the output of the retina? To answer this question, we performed in vivo 2-photons calcium imaging in retinal ganglion cells (RG
ePoster · Neuroscience