A biophysical counting mechanism for keeping time
Klavdia Zemlianova,Amitabha Bose,John Rinzel · COSYNE 2022
The ability to estimate and produce appropriately timed responses is central to many behaviors including speaking, dancing, and playing a musical instrument. A classical framework for estimating or producing a time interval is the pacemaker-accumulator model in which pulses of a pacemaker are counted and compared to a stored representation. However, the neural mechanisms for how these pulses are counted remain largely unaddressed. We present a biophysical model of how to keep count of cycles of a pacemaker clock. Our model utilizes a system of bistable Wilson-Cowan units asymmetrically connect
Thu, Mar 17, 2022