Topic: disease activity index

Ulcerative colitis, a chronic inflammatory bowel disease, is often associated with mental health disorders exacerbated by chronic stress. Environmental enrichment has been shown to alleviate stress and inflammation in mice, therefore we hypothesized that it may mitigate the adverse behavioral and neurobiological outcomes associated with experimental colitis. To study this, male and female mice were kept in 2 different housing conditions, conventional small cages (SE) or an enriched environment (EE), for 8 weeks. Subgroups were treated with dextran sulphate sodium (DSS) to induce experimental c