Topic: disinhibitory circuits

Recent advances in human intracranial recordings have significantly deepened our understanding of complex cognitive functions like working memory (WM) at the circuit level. While single-neuron analyses, primarily within the medial temporal lobes, have elucidated how individual neurons contribute to memory computation, the role of local field potential (LFP) dynamics in complementing single-unit activity during WM tasks remains poorly understood. To address this, we developed biologically plausible spiking recurrent neural networks (RNNs) trained on a delayed match-to-sample (DMS) task which in