Characterization of astroglia-noradrenergic neuron communication in the locus coeruleus
Wei-Chen Hung, Hsiu-Wen Yang, Ming-Yuan Min · FENS Forum 2024
Noradrenergic (NA) neurons originating from the locus coeruleus (LC) serve as the primary source of noradrenaline in the brain and play a critical role in arousal and cognitive functions. Previous studies have shown a potential link between astrocyte activity in the LC and emotional dysfunction, and suggested that astrocytes may influence NA neuron activity by modulating extracellular ion and neurotransmitter concentrations or by releasing gliotransmitters. However, there is currently no evidence for direct communication between astrocytes and NA neurons in the LC. In this study, we addressed
ePoster · Neuroscience