Integration of „environmental“ information in the neuronal epigenome
Geraldine Zimmer-Bensch · Functional Epigenetics in the Animal Model, Institute of Biology II, RWTH Aachen, Aachen, Germany
Wed, Aug 25, 2021 · 16:00 UTC
The inhibitory actions of the heterogeneous collection of GABAergic interneurons tremendously influence cortical information processing, which is reflected by diseases like autism, epilepsy and schizophrenia that involve defects in cortical inhibition. Apart from the regulation of physiological processes like synaptic transmission, proper interneuron function also relies on their correct development. Hence, decrypting regulatory networks that direct proper cortical interneuron development as well as adult functionality is of great interest, as this helps to identify critical events implicated