Topic: dominance behaviour

In mice, social dominance has been associated with anxiety trait and reduced stress resilience. However, the underlying mechanisms of this association remain unknown. Here, we tested the hypothesis that adult hippocampal neurogenesis may underlie dominance behaviour and anxiety.First, our observations in group-housed males unveiled that dominant mice exhibited heightened trait anxiety and vulnerability to stress when compared to their subordinate counterparts. Furthermore, we observed a reduction in hippocampal neurogenesis specifically within the ventral hippocampus of stressed dominant mice.