Topic: dopaminergic pathway

The spontaneous activity in the developing retina is essential for maturation of visual-associated brain area. The previous studies demonstrate that early light experience can also contribute to the development of visual system, but the effects and mechanisms are still largely unclear. Here we explored how the early light experience modulate retinal waves during the first postnatal week in mice. In the experiment, we used micro-electrode array (MEA) for electrophysiological recording. The retina from postnatal 3 to 8 days of mice were isolated under the dim red light and placed on MEA chip to