Topic: dorsal CA2 pyramidal neurons

The ability to remember and recognize other individuals is crucial for complex social behaviors. Although the hippocampus is known to be fundamental for social memory (Hitti & Siegelbaum, 2014), how this region represents and supports the two processes of social recognition - familiarity and recollection - remains unknown. We used microendoscopic calcium imaging to measure the activity of hippocampal dorsal CA2 pyramidal neurons (dCA2) - a region known for its importance in social memory - in mice interacting with novel and familiar conspecifics in different spatial contexts. Through a dec