Topic: dorsal column-medial lemniscus pathway

Proprioception is the sensation of the position and movement of the body in space. Forelimb proprioceptive afferents not only drive reflexes circuits in the spinal cord, but also ascend to the brain via projections to the external cuneate nucleus (Ecu) in the brainstem. Secondary neurons in the Ecu relay the incoming information via two major pathways: 1) the cuneo-cerebellar track which innervates the cerebellum and allows movement adaptation to unexpected perturbations and 2) the dorsal column-medial lemniscus pathway targeting the somatosensory cortex and allowing for the perception of prop