Representations of naturalistic behavior drift over hours at the level of single neurons and population dynamics
Aden Eagle, Paul Middlebrooks, Eric Yttri · COSYNE 2025
Spontaneous, naturalistic behaviors comprise most of an animal’s lifetime. However, understanding how the brain encodes complex naturalistic behavior remains a fundamental challenge in neuroscience. Decades of research has shown that performance on overtrained, task-based, goal-oriented behaviors can be decoded from neural activity recorded in areas of the corticostriatal axis, namely primary motor cortex (M1) and dorsal striatum (DS). More recently, single-unit responses during the execution of trained behaviors were found to be stable over a timescale of weeks in M1. However, it is currently
ePoster · Neuroscience