Anatomically heterogeneous pyramidal cells in supragranular layers of the dorsal cortex show the surface-to-deep firing frequency increase during natural sleep
Boglárka Bozsó, Robert G. Averkin, János Horváth, Sándor Bordé, Gábor Tamás · FENS Forum 2024
To explore how supragranular cortical pyramidal cells (Pyrs) are recruited during natural sleep, we applied a method of juxtacellular recording/labeling in freely moving rats. We asked how different Pyrs activate during sleep events such as down-to-up-state transition (DUt), spindle (SO), and REM sleep-related theta oscillations (ThO). Based on the polarity of the down-states (DS) recorded along with the cell firing, we divided Pyrs as superficial (negative DS, layer 2 – L2, n=35) or deep (positive DS, layer 3 – L3, n=35). Most of the Pyrs showed very sporadic firing behavior, with a lower ave
ePoster · Neuroscience