Cell-specific simultaneous optogenetic stimulation and inhibition utilizing dual-color striped organic LEDs
Jens Weber, Giuseppe Ciccone, Ilenia Meloni, Hans Kleemann, Karl Leo, Caroline Murawski · FENS Forum 2024
Optogenetics is a powerful tool that allows controlling cellular activity with light by optically activating either excitatory or inhibitory synaptic ion channels. In this project, we study the effect of simultaneous optogenetic activation and inhibition in the same cells of transgenic Drosophila larvae using dual-color organic light-emitting diodes (OLEDs). The OLEDs are patterned to sub-millimeter pixels with a high degree of light confinement, reaching optical power densities of 1 mW/mm−2, microsecond response speed and device heat‐up below 3 °C upon constant drive conditions at high bright
ePoster · Neuroscience