The functional role of the prelimbic microcircuits in encoding familiar and novel social stimuli
Anna Bryksa, Fahmida Haque, Joanna Borowska, Kinga Nazaruk, Joanna Jędrzejewska-Szmek, Szymon Łęski, Maciej Winiarski, Ewelina Knapska, Alicja Puścian · FENS Forum 2024
The role of the prelimbic part (PL) of the prefrontal cortex in encoding information about conspecifics remains poorly understood. Here we explore the functional role of various neuronal classes in the PL, including pyramidal cells (Pyr), parvalbumin- (PV+), somatostatin- (Sst+), and vasoactive intestinal peptide- (VIP+) expressing interneurons, in processing information about familiar and novel social stimuli.We employed chemo/optogenetics alongside automated behavioral testing in Eco-HAB®, an RFID-based system for ecologically relevant assessment of social behavior in group-housed mice. This
ePoster · Neuroscience