Pre- and postnatal maternal depressive symptoms associate with local connectivity of the left amygdala in 5-year-olds
Elena Vartiainen, Anni Copeland, Elmo P. Pulli, Venla Kumpulainen, Eero Silver, Olli Rajasilta, Ashmeet Jolly, Silja Luotonen, Hilyatushalihah K. Audah, Wajiha Bano, Ilkka Suuronen, Ekaterina Saukko, Suvi Häkkinen, Hasse Karlsson, Linnea Karlsson, Jetro J. Tuulari · FENS Forum 2024
Maternal pre- and postnatal depressive symptoms influence brain development in offspring through intrauterine conditions as well as ways of parenting and mother–child interaction. This study investigated whether maternal perinatal depressive symptoms associate with child’s whole brain regional homogeneity (ReHo) and seed-based connectivity of the bilateral amygdala at 5 years of age based on the sample available from FinnBrain Birth Cohort Study (N = 68; 40 female). Maternal depressive symptoms were assessed with the Edinburgh Postnatal Depression Scale (EPDS) at gestational week 24, 3, 6, and
ePoster · Neuroscience