Seminar · Sleep Medicine
Sleep deprivation and the human brain: from brain physiology to cognition”
Ali Salehinejad · Leibniz Research Centre for Working Environment & Human Factors, Dortmund, Germany
Tue, Aug 29, 2023 · 12:15 UTC
Sleep strongly affects synaptic strength, making it critical for cognition, especially learning and memory formation. Whether and how sleep deprivation modulates human brain physiology and cognition is poorly understood. Here we examined how overnight sleep deprivation vs overnight sufficient sleep affects (a) cortical excitability, measured by transcranial magnetic stimulation, (b) inducibility of long-term potentiation (LTP)- and long-term depression (LTD)-like plasticity via transcranial direct current stimulation (tDCS), and (c) learning, memory, and attention. We found that sleep deprivat