Transforming a head direction signal into a goal-oriented steering command
Elena Westeinde, Emily Kellogg, Paul Dawson, Jenny Lu, Lydia Hamburg, Benjamin Midler, Shaul Druckmann, Rachel Wilson · COSYNE 2023
To navigate, we must continuously estimate the direction we are headed in, and we must use this information to guide our path toward our goal (Schöne, 2014). Direction estimation is accomplished by ring attractor networks in the head direction system (Knierim et al., 2012, Hulse et al., 2020). However, we do not understand how the sense of direction is used to guide action. Drosophila connectome analyses (Rayshubskiy et al., 2020, Hulse et al., 2021) recently revealed two cell types (PFL2 and PFL3) that connect the head direction system to the locomotor system. These populations also receive a
Sat, Mar 11, 2023