Topic: egocentric vertex cells

Alzheimer’s disease (AD) is a neurodegenerative disease characterized by deficits in episodic memory processing and spatial navigation. Especially, the egocentric neural representation of space, which is important for constructing an egocentric cognitive map, is essential for spatial navigation. However, how spatial navigation deficits relate to egocentric neural representation of space remains unclear. The retrosplenial cortex (RSC) is one of the regions affected by amyloidosis in the early stages of AD and is well known for its role in egocentric spatial representation. Specifically, it cont