Topic: EI engrams

Network models of cortex typically focus on excitatory population dynamics, relegating inhibition to a support role. However, recent studies have shown that memories can be encoded by both excitatory and inhibitory neurons (EI engrams), adding to the evidence of the functional importance of inhibitory neurons beyond mere stabilization. The functional consequence of such EI engrams is unclear, and the synaptic plasticity rules that could sustain them are unknown. Here, we explore in silico a mechanism for EI engrams storage and recall to glean possible computational benefits of such engrams ove