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Topic: EI networks

ePoster
1 ePoster

In Biology and Biophysics

ePoster · Computational Neuroscience

The influence of the membrane potential on inhibitory regulation of plasticity predictions and learned representations

Patricia Rubisch, Melanie Stefan, Matthias Hennig · Bernstein Conference 2024

While inhibition is a building block of biological neural networks, its role in synaptic plasticity is yet to be fully understood. So far its role has only been addressed in rate and spike-timing based models (Wilmes et al., 2016; Agnes & Vogels,2024; Miehl & Gjorgijeva, 2022). Yet, experimental results show that the hyperpolarising effect of inhibition on the sub-threshold membrane potential can alter the expression of plasticity at excitatory synapses (Hayama et al. 2013; Paille et al. 2013). To address this gap, we explore the effects of inhibition in three voltage-dependent models: the vol