Topic: electron microscopy connectomics

Animals exhibit a stunning array of natural behaviors, many of which are innate and controlled by intricate neural circuits genetically specified. In the fruit fly, connectomics work has revealed precise patterns of neuronal connectivity and their computational potential. However, we lack a molecular understanding of how such circuit connectivity is established with synaptic specificity, in part because it remains challenging to define the molecular landscape and interactions at subcellular resolution in intact tissue. Taking advantage of the well-defined and accessible Drosophila motion visio