Topic: eloquent cortex

Having a patient specific mapping of the eloquent cortex is crucial for patients undergoing resective surgery. Non-invasive neuroimaging modalities like magnetoencephalography (MEG) are increasingly used for pre-surgical mapping due to high temporal resolution. Phase-amplitude coupling (PAC), a form of cross-frequency coupling, involves the modulation of high-frequency amplitude by the phase of low-frequency oscillations. PAC observed during tasks reflect interactions between microscale and macroscale neural ensembles. The objective of this study was characterizing whether PAC differs during t