Extracellular vesicles: An exploration into the bi-directional crosstalk of endothelial cells and astrocytes at the blood-brain barrier
Natalija Aleksejenko, Keith D. Rochfort, Philip M. Cummins, Janosch P. Heller · FENS Forum 2024
Endothelial cells (ECs) tightly regulate the passage of ions, molecules, and cells from the blood into the brain and vice versa as part of the blood-brain barrier (BBB). Astrocytes aid in the formation and maintenance of the BBB. Aside from direct communication, astrocytes and ECs also release extracellular vesicles (EVs) to communicate with each other and other cells. EVs carry genetic information, proteins, and other signalling molecules. This cargo changes relative to the donor cell state, which can influence different processes in recipient cells.This project investigates this bi-direction
ePoster · Neuroscience