Exploring the influence of maternal prenatal depressive symptoms and hair cortisol concentration on infant corpus callosum integrity
Isabella Mariani Wigley, Paula Mustonen, Linnea Karlsson, Saara Nolvi, Noora M. Scheinin, Susanna Kortesluoma, Massimiliano Pastore, Bárbara Coimbra, Ana João Rodrigues, Nuno Sousa, Hasse Karlsson, Jetro J Tuulari · FENS Forum 2024
The present study explores the interplay between maternal prenatal depressive symptoms and cortisol levels in predicting infant brain development, with a focus on neonatal corpus callosum (CC) integrity. Leveraging data from the FinnBrain Birth Cohort Study, we involved 40 mother-infants dyads. We conducted DTI imaging on 2-5-week-old infants to estimate fractional anisotropy (FA) values in CC regions (Genu, Body, and Splenium) and evaluated maternal prenatal cortisol levels through hair cortisol concentration (HCC). The latter reflects cortisol concentration over the last five months of pregn
ePoster · Neuroscience