Patient-specific EEG simulation of focal and generalized epilepsy with a virtual human brain based on neurophysiology
Pascal Benquet, Maxime Yochum, Elif Köksal-Ersöz, Anna Kaminska, Rima Nabbout, Isabelle Merlet, Matthieu Aud'Hui, Patrick Van Bogaert, Mathieu Kuchenbuch, Fabrice Bartolomei, Fabrice Wendling · FENS Forum 2024
Context: Scalp electroencephalography (EEG) is the gold standard method for recording interictal and ictal activity in epileptic patients. Dynamic and topography of EEG signals are patient-specific. They depends on the individual's brain anatomy, type of the lesion, propagation of the epileptic activity within large-scale epileptic networks. How can we interpret epileptiform events from a neurophysiological perspective? To answer this, we developed a whole brain model based on neuronal physiology that can be used to interpret patient-specific EEG signals.Methods. We developed a whole brain neu
ePoster · Neuroscience