Topic: epiretinal stimulation

Understanding the retina in health and disease is a key issue for neuroscience and neuroengineering applications such as retinal prostheses. Although the processing of visual information in the healthy retina has been studied in detail, no comprehensive computational model exists that captures the many cell-level and network-level biophysical changes common to retinal degenerative diseases. To address this challenge, we developed a biophysically detailed model of the retinal circuitry and simulated the network-level response to both light and electrical stimulation. The model included 11,138 c