Two distinct ways to form long-term object recognition memory during sleep and wakefulness
Max Harkotte, Anuck Sawangjit, Carlos Oyanedel, Niels Niethard, Jan Born, Marion Inostroza · FENS Forum 2024
Memory consolidation is promoted by sleep. However, there is also evidence for consolidation into long-term memory during wakefulness via processes that preferentially affect nonhippocampal representations. We compared, in rats, the effects of 2-h postencoding periods of sleep and wakefulness on the formation of long-term memory for objects and their associated environmental contexts. We employed a novel-object recognition (NOR) task, using object exploration and exploratory rearing as behavioral indicators of these memories. Remote recall testing (after 1 wk) confirmed significant long-term N
ePoster · Neuroscience